Application of propolis in veterinary medicine

China is a big bee-keeping country and its honey production and export volume ranks first in the world. There are about 6 million boxes of bee-keeping in the country, each box can take 100 grams of propolis, and the annual amount of propolis can reach 600,000 kilograms. Propolis resources are very promising. Propolis has significant biological effects such as immune enhancement. It can extend the immunity period and the preservation period of the vaccine. Propolis has a killing and inhibiting effect on Pasteurella, so it can be used as an emergency control in the epidemic area, and there is no need to add antibacterial antibacterial agents in the vaccine; propolis has the effect of tranquilizing and detoxifying and can reduce the stress of poultry; Propolis can stimulate protein synthesis and can help increase egg production rate. Propolis is non-antigenic, non-allergic, non-toxic, and has anti-cancer effects. 1. Propolis can enhance immune function and protect body health. Experiments have shown that propolis has the same immune-enhancing effect as white oil. The chicken E. coli multivalent propolis inactivated vaccine prepared with propolis as adjuvant is safe to use, has good immunity, the protection rate is 100%, and the immunization period is 6 months. After the immunization, the weight gain of chickens is accelerated and the egg production rate is increased. With the decrease in mortality. With propolis as an immunopotentiator, the cholera inactivated bacterin vaccine produced by the system has no swelling, pain, necrosis, etc. after immune injection to chickens, ducks and geese over 2 months of age. There is an 80% protection rate, reaching 100% on the 7th day. 2. Both mildew and sterilizing The hive inside the beehive is dark and damp, and the temperature is high. It is the best environment for mold and spoilage. However, the moldy spoilage never occurs in the beehive throughout the year, which proves that the propolis contains fungi that can substance. With 0.25% to 10% propolis liquor, there are inhibitory effects on 17 kinds of pathogenic bacteria, among which the antibacterial effect against Shigella flexneri and β-hemolytic streptococcus is stronger, followed by Salmonella typhi Salmonella, Salmonella choleraesuis, Salmonella abortus, Pneumococcal infection, fowl cholera, Pasteurella pneumoniae, Streptococcus equi, Salmonella typhimurium, Pseudomonas aeruginosa have inhibitory effects. In addition, the propolis ethanol solution has inhibitory effects on Bacillus subtilis, Staphylococcus aureus, Gram-negative bacteria and Mucor, Rhizopus, Streptomyces subtilis, actinomycetes and brewer's yeast, and can be used as antibacterial agents for edible fungi. Without contaminating the product. 3. Sterilization and anti-inflammatory treatment of diseases Propolis is used as a traditional Chinese medicine for anti-toxicity, bactericidal, anti-inflammatory, analgesic, itching, deodorant, astringent, myogenic, promote wound healing, etc. Veterinary clinics are also used to treat livestock and poultry diseases. . When diarrhea, enteritis, and diarrhea occur in cattle, horses, and pigs, 3 grams of propolis is used per 10 kilograms of body weight. The curative effect is about 90%. For chicken typhoid and chicken white fleas, it is mixed with propolis and rice bran to mix in thick rice soup. , Feed each time in the morning and evening, or grab the chicken directly into the propolis, 1 g per chicken, once a day, even feed 3 to 5 days, that can be cured. In surgery, propolis has good effects on wounds and burns. For example, propolis ointment is used for the treatment of foot-and-mouth disease. The healing rate is 1.5 to 2 times faster than sulfa ointment, camphor oil or tar, no purulent phenomenon, and no scars are left; 15% or 20% propolis ointment; treatment of ducklings umbilical cord 2 to 3 days, umbilical cord dryness falls off and more; with 0.5 grams of propolis, quinmasamine sulfur salt, cocoa butter 5 grams, made of suppository, treatment of trichomoniasis caused cattle abortion Resulting endometritis, after 7 to 8 days, returned to normal, trichomoniasis disappeared, the cure rate was 100%; treatment of livestock and poultry burns, use 1 part of propolis, soaked in 5 parts of 95% alcohol, 7 days after the slag, with disinfection The gauze dipped in liquid was applied at the burn site, light one time, and heavy ones 2 to 3 times healed without Pseudomonas aeruginosa infection. 4. Anti-corrosion preservation, high-efficiency and low-cost propolis In addition to anti-microbial, there are natural and efficient anti-corrosion preservation effect. For example, if citrus fruit is sprayed with 0.25% to 1% of propolis extract, the original color and flavor will remain unchanged after 3 months, while many of the non-sprayed fruits will have decayed and rotted. Eggs were smeared with 10.4% propolis ethanol extract. After 107 days of storage, egg weight loss was 2.25%. After eggs were stored for 60 days in the control group, the protein became thin and the eggs became dark and stinky, because the propolis formed a film outside the eggshell. The shell combines defense, delaying the emergence of respiratory transition and reducing the loss of nutrients.

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