First aid method for spray drying equipment in case of failure

When the effect of the air filter of the centrifugal spray dryer is poor, it is necessary to improve the air filtration efficiency, clean or replace the filter in time; the coke powder is mixed into the product during production; in this case, the coke powder at the hot air inlet is checked. Adjust the airflow rate to overcome eddy currents or use water-cooled or air-cooled jackets around the hot air distributor outlet. Or the feed liquid has a high impurity level, and the liquid is filtered before spraying because the equipment is not clean and the equipment needs to be cleaned.

If the product is too fine in the re-production process, the product yield is low, and the running loss is large; most of them are due to the low efficiency of the cyclone separator. It is necessary to check whether the cyclone separator is deformed by tapping, and check the airtightness of the cyclone separator. Whether there is accumulation or blockage inside and outside the outlet. It may also be because the bag filter interface is loose or the bag is perforated, the interface needs to be repaired, and the bag is regularly checked.

If the speed of the centrifugal sprayer is reduced, the current is increased, the feed rate is too high, and it is overloaded. It is necessary to reduce the supply amount or the mechanical failure of the sprayer and the motor; or stop the spray, check and troubleshoot.

If the flow rate of the sprayer fluctuates greatly, most of them are due to motor defects, so the mechanical resonance phenomenon of the sprayer and the motor is generated. At this time, the motor should be closely inspected.

LCZ696 (Valsartan/sacubitril) is a combination drug for use in heart failure developed by Novartis. It consists of the angiotensin receptor blocker valsartan and the neprilysin inhibitor sacubitril, in a 1:1 mixture by molecule count. It may be used instead of an ACE inhibitor or an angiotensin receptor blocker in people with heart failure with reduced ejection fraction. The combination is sometimes described as an "angiotensin receptor-neprilysin inhibitor" (ARNi).
It was approved under the FDA's priority review process on July 7, 2015. It is also approved in Europe.
We produce a series of complete intermediates for LCZ696, intermediate I (CAS No. 1426129-50-1) and intermediate II (CAS No. 1012341-50-2) etc.

All of our products are with stable production and strict quality control, making sure your experience with Sunshine Biotech is always enriching, satisfying and fulfilling.

Pharmaceutical Intermediates

Lcz696 Intermediates

Lcz696 Intermediates,Cas 1426129-50-1,Cas 1012341-50-2,High Purity Lcz696 Intermediate

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