Antihypertension Drug Telmisartan CAS: 144701-48-4 White Powder

Antihypertension Drug Telmisartan CAS: 144701-48-4 White Powder

Description:

Telmisartan is a benzimidazole derivative and a non-peptide angiotensin II receptor antagonist with antihypertensive property. Telmisartan selectively antagonizes angiotensin II binding to the AT1 subtype receptor, located in vascular smooth muscle and adrenal gland. The antagonism results in vasodilation and inhibits the angiotensin II-mediated aldosterone production, which in turn leading to a decrease in sodium and water as well as an increase in potassium excretion leading to a subsequent reduction in blood pressure.

Basic Details:

Chemical name: Telmisartan
MF: C33H30N4O2
MW: 514.63
CAS: 144701-48-4
Appearance: White powder
Package: 25KG/Drum
Usage: antihypertension medication

COA:
 
What is telmisartan, and how does it work (mechanism of action)?

Telmisartan is a member of a family of drugs called angiotensin receptor blockers (ARBs), which includes losartan (Cozaar), valsartan (Diovan), irbesartan (Avapro), and candesartan (Atacand). Angiotensin, formed in the blood by the action of angiotensin converting enzyme (ACE), is a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on muscle cells of blood vessels. Angiotensin's attachment to the receptors causes muscle cells to shorten and narrow the blood vessels (vasoconstrict), which leads to an increase in blood pressure (hypertension). Telmisartan blocks the angiotensin receptor. By blocking the action of angiotensin, telmisartan widens blood vessels (vasodilate) and reduces blood pressure. Telmisartan was approved by the FDA in November 2000.

DOSAGE AND ADMINISTRATION:

Hypertension

Dosage must be individualized. The usual starting dose of MICARDIS tablets is 40 mg once a day. Blood pressure response is dose-related over the range of 20 to 80 mg [see Clinical Studies].

Most of the antihypertensive effect is apparent within 2 weeks and maximal reduction is generally attained after 4 weeks. When additional blood pressure reduction beyond that achieved with 80 mg MICARDIS is required, a diuretic may be added.

No initial dosage adjustment is necessary for elderly patients or patients with renal impairment, including those on hemodialysis. Patients on dialysis may develop orthostatic hypotension; their blood pressure should be closely monitored.

MICARDIS tablets may be administered with other antihypertensive agents.

MICARDIS tablets may be administered with or without food.




Packaging:

We have professional team for package and shipment.Special way to ship 100 ml to 100L liquids at one time to your country.Fast and discreet shipment could be arranged for customs pass Guaranteed.

Competitive Advantage:
 
We supply a variety of chemicals with competitive price and high quality including:
Food additive
Feed additive
Pharmaceutical raw materials
 
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Pesticides
Veterinary medicine
Flavoring and essence
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Paint and coating
Inorganic chemicals
Organic chemicals
Amino acid,
Vitamins.

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How to proceed order:

1.Please let me know the items you are looking for, quantity, and the destination country.
2.We send the detailed price of our product and offer the suitable shipping method for your reference.
3.You confirm the order and pay money 100% in advance and send us the detailed address.
4.We will pack your parcel and arrange to shipment according to your requirements
5.Once parcel is sent,I will offer you parcel's picture,tracking number and tracking website.
6.After you receiving parcel,we will offer you best after-sale.

If you have any questions, please feel free to contact me:

Miss Debbie: +8618872220738 Antihypertension Drug Telmisartan CAS: 144701-48-4 White Powder

Description:

Telmisartan is a benzimidazole derivative and a non-peptide angiotensin II receptor antagonist with antihypertensive property. Telmisartan selectively antagonizes angiotensin II binding to the AT1 subtype receptor, located in vascular smooth muscle and adrenal gland. The antagonism results in vasodilation and inhibits the angiotensin II-mediated aldosterone production, which in turn leading to a decrease in sodium and water as well as an increase in potassium excretion leading to a subsequent reduction in blood pressure.

Basic Details:

Chemical name: Telmisartan
MF: C33H30N4O2
MW: 514.63
CAS: 144701-48-4
Appearance: White powder
Package: 25KG/Drum
Usage: antihypertension medication

COA:
 
What is telmisartan, and how does it work (mechanism of action)?

Telmisartan is a member of a family of drugs called angiotensin receptor blockers (ARBs), which includes losartan (Cozaar), valsartan (Diovan), irbesartan (Avapro), and candesartan (Atacand). Angiotensin, formed in the blood by the action of angiotensin converting enzyme (ACE), is a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on muscle cells of blood vessels. Angiotensin's attachment to the receptors causes muscle cells to shorten and narrow the blood vessels (vasoconstrict), which leads to an increase in blood pressure (hypertension). Telmisartan blocks the angiotensin receptor. By blocking the action of angiotensin, telmisartan widens blood vessels (vasodilate) and reduces blood pressure. Telmisartan was approved by the FDA in November 2000.

DOSAGE AND ADMINISTRATION:

Hypertension

Dosage must be individualized. The usual starting dose of MICARDIS tablets is 40 mg once a day. Blood pressure response is dose-related over the range of 20 to 80 mg [see Clinical Studies].

Most of the antihypertensive effect is apparent within 2 weeks and maximal reduction is generally attained after 4 weeks. When additional blood pressure reduction beyond that achieved with 80 mg MICARDIS is required, a diuretic may be added.

No initial dosage adjustment is necessary for elderly patients or patients with renal impairment, including those on hemodialysis. Patients on dialysis may develop orthostatic hypotension; their blood pressure should be closely monitored.

MICARDIS tablets may be administered with other antihypertensive agents.

MICARDIS tablets may be administered with or without food.




Packaging:

We have professional team for package and shipment.Special way to ship 100 ml to 100L liquids at one time to your country.Fast and discreet shipment could be arranged for customs pass Guaranteed.

Competitive Advantage:
 
We supply a variety of chemicals with competitive price and high quality including:
Food additive
Feed additive
Pharmaceutical raw materials
 
Cinnamate series
Pesticides
Veterinary medicine
Flavoring and essence
Plant extract
Paint and coating
Inorganic chemicals
Organic chemicals
Amino acid,
Vitamins.

Other products you may like.
Antineoplastic Crude Drug
L-Triiodothyronine(T3)(CAS No:55-06-1)
Anastrozol(Arimidex)(CAS:120511-73-1)
Trilostane(CAS:13647-35-3)
Formestan(CAS:566-48-3)
(Aromasin)(CAS:107868-30-4)

Weight Loss Drug
 
L(-)-Carnitine(CAS:541-15-1)
Rimonaban* (CAS:158681-13-1)

Local Anaesthetic Drug
 
 
 
 

Estrogen Hormone
Progesterone (CAS:57-83-0)
Estradiol (CAS:50-28-2)
Estriol (CAS:50-27-1)
Estradiol valerate (CAS:979-32-8)
Diethylstilbestrol (CAS:56-53-1)
Hexestrol (CAS:84-16-2)

How to proceed order:

1.Please let me know the items you are looking for, quantity, and the destination country.
2.We send the detailed price of our product and offer the suitable shipping method for your reference.
3.You confirm the order and pay money 100% in advance and send us the detailed address.
4.We will pack your parcel and arrange to shipment according to your requirements
5.Once parcel is sent,I will offer you parcel's picture,tracking number and tracking website.
6.After you receiving parcel,we will offer you best after-sale.

If you have any questions, please feel free to contact me:

Miss Debbie: +8618872220738

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